The Head of the Virgin in Three-Quarter View Facing Right

This drawing features four figures closely intertwined in a pyramidal composition, rendered with soft shadows and delicate line work. Saint Anne watches over Mary with a peaceful expression while the two children play at the side, creating a sense of fluid movement between the bodies. A large open book is visible to the right, suggesting the presence of holy scripture or prophetic wisdom within the scene.

The work reflects Leonardo's investigation into the organic forces of nature and the 'motions of the mind,' aligning with Renaissance natural philosophy. The complex, geometric arrangement of the figures embodies Neoplatonic ideals of finding divine mathematical order within the biological forms of the human body.