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Moffett, Thomas · 1578

XXVII.
It has also pleased me to add these particular anodynes, partly because there are many reliable accounts original: "axiaopista on phus" held to be true, and partly because they may be applied without harm, and we are forced daily to approve of many things far more absurd.
XXVIII.
Universal anodynes, however, are always most dangerous, unless they are administered correctly, that is, with judgment and order. Therefore, lest someone by chance misuse such excellent medicines, which by the testimony of Erophilus are as if they were the hands of the gods, one must state when, to whom, how much, and what kind of anodyne it is appropriate to give.
XXIX.
Galen teaches the first in these words: "The physician encounters pain in various and different ways," etc. There is, he says, a twofold method of resisting pain: one by which we cater to the comforts of the bedridden, the other which obeys science and method. The latter is served by two classes of medicines: those from maturing, softening, and dispersing herbs, etc., and subsequently the anodynes and sleep-inducing ones, by whose powers all pain, as if cast into prison or chains, rests.
XXX.
The former, namely the dispersers, are always appropriate; but the latter are to be used only in those pains whose bitterness and magnitude announce nearly certain death. Such as in gout or a colic attack.