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Whoever are nephritic are not healed after forty years. Nephritic pains and those that occur around the bladder are healed with difficulty in old men; indeed, they die with these affections. Hippocrates, book 6, aphorism 6.
In whomsoever bubbles or blisters float on the urine, it signifies that the nephritic illness will be long, book 7, aphorism 34.
The treatment must be established by a certain method, through diet, surgery, and medicines.
Diet consists in the correct administration of the six non-natural things a reference to the six factors in Galenic medicine: air, food/drink, sleep/waking, motion/rest, excretion/retention, and mental affections.
The air, therefore, should not be thick, nor cloudy, nor rainy, but pure and temperate.
Let the food be of good juice, easy to digest, and by no means thick or sticky, or salty. Let the drink be thin, white wine: he should avoid stagnant and very cold waters. Hippocrates, book 6, On Popular Diseases, commentary 3, text 15. Aetius, book 11, chapter 6.
Idleness is to be avoided: walks and moderate exercises are appropriate, which are able to exercise the body according to the reason of the age, habit, and strength of the sick person. Hippocrates, book 6, On Popular Diseases, commentary 1.
Sleep, as much as possible, should be induced a little longer than usual, on account of digestion, so that poor digestions crude or undigested matter are avoided.